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. Author manuscript; available in PMC: 2020 Sep 16.
Published in final edited form as: Behav Brain Res. 2019 May 13;370:111943. doi: 10.1016/j.bbr.2019.111943

Fig. 4.

Fig. 4.

Circadian dependent effects of caffeine on prepulse inhibition, (a) During the light cycle %PPI increased as the volume in decibels increased and was significantly higher in CAF than control mice (#P <0.05 for main effect of treatment by two-way ANOVA; n=15 per treatment), (b) During the dark cycle %PPI was significantly reduced in CAF mice (#P < 0.05 for main effect of treatment by two-way ANOVA: control n=9, CAF n=8). (c) Acoustic startle reactivity was not significantly different with CAF treatment or between light and dark cycle.