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Mean values and standard errors of the percentage of MMP-8 (a) in noninfected, (b) infected wounds, and collagen in noninfected (c), and infected wounds (d). Wounds are infected separately with 10 μL of S. aureus (ATCC 25923) and P. aeruginosa at 108 Colony Forming Unit (CFU). The data showed significant depletion in the activity of MMP-8 and increase in the level of collagen deposition in wounds of control and treated animals at 3, 6, 9, 15, and 21 postoperative days.
