Table 4.
Clinical characteristics in type 2 diabetic patients with normoalbuminuria, microalbuminuria, and macroalbuminuria.
| Normoalbuminuria | Microalbuminuria | Macroalbuminuria | p | |
|---|---|---|---|---|
| Number (n) | 131 | 90 | 38 | |
| Age (years) | 53.91 (12.21) | 52.75(12.72) | 55.55(13.98) | NS |
| Sex (male/female) | 90/41 | 57/33 | 30/8 | NS |
| Duration of diabetes (years)△ | 2(0.8,9) | 6(5,11)∗ | 6.5(3,13.5)∗ | <0.001 |
| Waist circumference (cm) | 86.63 (11.12) | 88.53(8.53) | 86.7(8.12) | NS |
| BMI (kg/m2) | 24.91(3.46) | 25.71(3.6) | 25.73(2.7) | NS |
| SBP (mmHg) | 125.01(13.26) | 126.74(12.96) | 125.84(10.58) | NS |
| DBP (mmHg) | 78.37(7.47) | 79.10(6.24) | 80.02(5.21) | NS |
| Glycated hemoglobin (%) | 8.03(1.45) | 8.69(1.85)∗ | 9.42(1.73)∗ | <0.001 |
| Triglycerides (mmol/l) △ | 1.62(1.15,2.21) | 3.0(1.68,4.51)∗ | 2.00(1.05,5.32)∗ | <0.001 |
| Total cholesterol (mmol/l) | 4.62(1.03) | 4.88(0.98) | 4.88(0.86) | NS |
| HDL cholesterol (mmol/l)△ | 1.07(0.30) | 1.02(0.28) | 1.05(0.24) | NS |
| LDL cholesterol (mmol/l) | 2.77(0.75) | 2.88(0.83) | 3.03(0.68) | NS |
| Scr (umol/l) | 55.53(13.58) | 68.15(25.12)∗ | 80.84(32.89)∗# | <0.001 |
| hs-CRP (mg/L) △ | 3.6(1.2,6.6) | 5.4(2.1,9.05)∗ | 6.3(3.6,12.5)∗ | 0.001 |
| Chemerin (ng/ml) | 97.69(40.27) | 112.93(43.40)∗ | 135.08(65.42)∗# | <0.001 |
| Medication | ||||
| Oral hypoglycemic agents | 33(25.1%) | 31(34.4%) | 9(23.7%) | NS |
| Insulin | 98(74.9%) | 59(65.6%) | 29(76.3%) | NS |
| Hypertension (%) | 71(54.19%) | 57(63.3%) | 26(68.42%) | NS |
Numerical variables are expressed as the mean with SD and median (interquartile range). Categorical variables were presented as number (percentage). P-value for difference between the groups was calculated from the analysis of one-way ANOVA, ∗vs. Normoalbuminuria group, and # vs. Microalbuminuria group.
BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; Scr, serum creatinine; hs-CRP, high sensitivity C-reactive protein; NS, not significant.
△Natural logarithmic transformation was used in analysis.