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. 2019 Jul 22;10:1638. doi: 10.3389/fmicb.2019.01638

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Copyright © 2019 Yao, Gao, Xu, Chen, Yang, Han, He, Li, Zhou and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Time-killing curves of amoxicillin against S. aureus at different doses in the tissue-cage model. Amoxicillin at doses of 5, 10, 20, and 30 mg/kg body weight (bw) twice daily for 2.5 days (A1–A4) and 5, 10, 20, and 30 mg/kg bw once daily for 5 days (B1–B4); n represents the number of animals per group.