TABLE 2.
Response profiles defined by trajectory analysis (n = 344)
| Correspondence with endpoint class: (% of total n = 251 completers) |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Baseline controlled (bc-ΔHRSD) class |
N | Total (%) |
Baseline HRSD total |
Fitted baselinea |
Fitted ΔHRSD/wk |
Fitted corr w/ baselineb |
Nonresponder (< 30%) |
Partial Responder (30–50%) |
Response (> 50%) |
Remission |
| Early remission | 43 | 12.5 | 20.6 (3.6) | 14.2 | −1.27 | 0.239 | 0 | 0 | 3(1.2%) | 32 (12.7%) |
| Delayed remission | 24 | 7.0 | 21.6 (4.3) | 20.6 | −1.67 | 0.211 | 0 | 0 | 3(1.2%) | 19 (7.6%) |
| Gradual remission | 111 | 32.3 | 19.2 (3.5) | 16.1 | −0.95 | 0.453 | 3 (1.2%) | 7 (2.8%) | 26 (10.4%) | 53 (21.1%) |
| Minimal response | 138 | 40.1 | 19.9 (4.0) | 19.0 | −0.62 | 0.536 | 22 (8.8%) | 30 (12.0%) | 21 (8.4%) | 10 (4.0%) |
| No response | 28 | 8.1 | 18.4 (3.0) | 18.5 | −0.03 | 0.552 | 21 (8.4%) | 1 (0.4%) | 0 | 0 |
| Total | 46 (18.3%) | 38 (15.1%) | 53 (21.1%) | 114 (45.4%) | ||||||
a
Fitted baseline for bc-ΔHRSD class is computed for baseline mean average HRSD17 for that group.
b
Represents fitted correlation between baseline HRSD and ΔHRSD.