Table 1.
Number | 39 |
Age, median (range) | 63 (36–78) |
Sex | |
Male | 34 |
Female | 5 |
ECOG | |
0 | 10 |
1 | 29 |
Liver cirrhosis | |
Yes | 26 |
No | 13 |
Cause of liver disease | |
HBV | 7 |
HCV | 21 |
Baseline Child–Pugh score | |
5 | 16 |
6 | 7 |
7 | 3 |
BCLC stage | |
B | 9 |
C | 30 |
Extrahepatic disease | |
Yes | 17 |
No | 22 |
Prior sorafenib | |
Yes/no | 27/12 |
Discontinue due to PD/intolerance | 23/4 |
Other systemic therapies | 10 |
Other previous interventions | |
TACE | 13 |
Surgery | 5 |
Ablation | 6 |
Outcome analysis | |
Non-evaluable | 5 |
Non-responder | 15 |
Responder | 19 |
CR | 1 |
PR | 7 |
SD | 15 |
PD | 11 |
ECOG Eastern Cooperative Oncology Group, HBV Hepatitis B virus, HCV Hepatitis C virus, BCLC Barcelona Clinic Liver Cancer, PD progressive disease, TACE transarterial chemoembolization, CR complete response, PR partial response, SD stable disease