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. Author manuscript; available in PMC: 2020 Jan 25.
Published in final edited form as: Nat Neurosci. 2019 Jul 25;22(8):1248–1257. doi: 10.1038/s41593-019-0457-5

Fig. 2. α-Synuclein spreads in a dynamic spatiotemporal pattern throughout the mouse brain.

Fig. 2

a, Representative quantitative pS129 α-Synuclein pathology plots and images are shown for 1-, 3- and 6-month timepoints (scale bar=50 μm). Plots display mean +/− standard error. b, Heat map of regions affected with α-Synuclein pathology. The names of the associated areas are plotted onto identical maps in the supplementary material. The color scale represents log-transformed mean percentage area occupied with α-Synuclein pathology. n (number of mice), 1 MPI=4, 3 MPI=6, 6 MPI=6.