Table 1.
Characteristics of patients with human papillomavirus (HPV)-associated oropharyngeal cancer.
| N(%) | |
|---|---|
| Total number | 37 |
| Age | |
| 30-39 | 1 (3) |
| 40-49 | 7 (19) |
| 50-59 | 15 (41) |
| 60-69 | 7 (19) |
| ≥70 | 7 (19) |
| Gender | |
| Female | 4 (11) |
| Male | 33 (89) |
| Race/Ethnicity | |
| White | 33 (89) |
| Black/Hispanic/Other | 4 (11) |
| Tobacco use | |
| Never | 12 (43) |
| Current | 2 (7) |
| Former | 14 (50) |
| Alcohol use | |
| Current | 18 (67) |
| Former | 9 (33) |
| Annual household income | |
| <$50,000 | 3 (12) |
| $50,000 - $150,000 | 14 (54) |
| ≥$150,000 | 9 (35) |
| Education | |
| Less than advanced degree | 8 (29) |
| Advanced degree | 20 (71) |
| HPV tumor status | |
| P16-positive | 37 (100) |
| HPV ISH-positive (among tested)a | 22 (100) |
| HPV16 ISH-positive (among tested) | 19 (86) |
| AJCC 7th Ed. tumor stage | |
| T1 | 19 (51) |
| T2 | 13 (35) |
| T3 | 2 (5) |
| T4 | 3 (8) |
| AJCC 7th Ed. nodal stage | |
| N0 | 1 (3) |
| N1 | 4 (11) |
| N2 | 31 (83) |
| N3 | 1 (3) |
| Treatment | |
| RT | 1 (3) |
| CRT | 16 (43) |
| Surgery | 1 (3) |
| Surgery + RT | 9 (24) |
| Surgery + CRT | 10 (27) |
| Median FACT-G score (IQR)b | 81 (65-92) |
| Median Regret score (IQR)c | 5 (0-20) |
IQR, interquartile range; HPV, human papillomavirus; ISH, in situ hybridization; RT, radiation therapy; CRT, chemoradiotherapy; FACT-G, Functional Assessment for Cancer Treatment – General
a
positive by RNA in situ hybridization for 18 high-risk HPV genotypes.
b
range, 0-108
c
range, 0-100