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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Stroke. 2019 Apr;50(4):783–788. doi: 10.1161/STROKEAHA.118.024143

Table 2.

Longitudinal Association of Incident Atrial Fibrillation (AF) with Brain MRI Abnormalities in the ARIC Ancillary MRI Substudy, 1993–2006

Brain MRI Variable No AF (n-934) AF (n=29) Model 1 Model 2
N (%) N (%) Odds Ratio (95% CI) P Odds Ratio (95% CI) P
Worsening Sulcal Grade 634 (68%) 26 (90%) 3.65 (1.08–12.3) 0.04 3.56 (1.04–12.2) 0.04
Worsening Ventricular Grade 691 (74%) 28 (97%) 8.61 (1.16–63.7) 0.04 9.34 (1.24–70.2) 0.03
Increase in Subclinical Cerebral Infarctions 172 (18%) 12 (41%) 2.92 (1.36–6.28) 0.006 3.08 (1.39–6.83) 0.006

Logistic regression was used for dichotomous outcomes to calculate odds ratios.

Model 1: Adjusted for age, race and sex

Model 2: Adjusted for age, race, sex, center, education, occupation, cigarette smoking, body mass index, hypertension, diabetes, prevalent coronary heart disease, prevalent congestive heart failure, anticoagulant medication use

MRI=Magnetic Resonance Imaging, SD= Standard Deviation, cm3= Cubic Centimeters