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. 2019 Jul 29;9:11001. doi: 10.1038/s41598-019-47311-4

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Example of network outputs using blue irradiance and wrist skin temperature inputs. (A) Predicted melatonin rhythm for one participant using the network trained on fixed sleep data. Prediction error is 11.69 minutes. (B) Predicted aMT6s rhythm for one participant using the non-shift work network trained on fixed and habitual sleep data. Prediction error is 4.52 minutes. (C) Predicted aMT6s rhythm for one participant on the night shift schedule, predicted using the SWnight network. Prediction error is 205.9 minutes. Black represents the fitted reference aMT6s waveform, blue represents the predicted aMT6s waveform, red represents the fitted cosine curve to predicted waveform.