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. 2019 Jul 29;9:10915. doi: 10.1038/s41598-019-47456-2

Table 1.

Clinical characteristics of study subjects.

Total population Subjects with very high HDL-C p
(n = 13545) (n = 42)
Age, years 60.4 ± 10.6 54.1 ± 12.8 <0.0001
Male 6722 (50) 16 (38) 0.12
Medical history
  Hypertension 7234 (53) 9 (21) <0.0001
  Diabetes mellitus 2293 (17) 2 (5) <0.0001
  Smoking 2004 (15) 11 (26) 0.09
  Coronary artery disease 4741 (35) 3 (7) <0.0001
  Body mass index, kg/m2 24.8 ± 3.1 22.6 ± 4.2 0.002
Laboratory values, mg/dL
  Total cholesterol 189 ± 43 220 ± 38 <0.0001
  TG 117 (83) 62.5 (27) <0.0001
  HDL-C 48.8 ± 14.7 110.1 ± 12.6 <0.0001
  LDL-C 115 ± 38 101 ± 35 0.02

Data are presented as mean ± standard deviation or number (%); HDL-C: high-density lipoprotein-cholesterol; TG: triglyceride; LDL-C: low-density lipoprotein-cholesterol.