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. 2019 May 21;17:44. doi: 10.18332/tid/106089

Table 4.

Sensitivity analysis of results of risk of having a small-for-gestational-age neonate, corrected for misclassification of exposure, Little Rock, Arkansas, 2015–2017 (N=120 from Table 2, N=23 exposed to ENDS, and N=97 self-reported as unexposed)

Biomarker criteria versus self-report (type of users) Source of estimates of sensitivity and specificity (n*) Sensitivity of exposure Specificity of exposure Any ENDS current use risk ratio** ( 95% CI)
Self-report This study Naïve Naïve 2.3 (0.9–5.6)
Hair nicotine ≥2.77 ng/mL (smokers/ENDS vs unexposed) This study (76) 0.83 0.85 6.5 (2.5–15.0)
Hair nicotine ≥2.77 ng/mL (smokers vs passive non-smokers) Kim (289) 0.84 0.82 8.5 (3.3–19.5)
*

Excludes secondhand exposure to smoke or aerosols from others for the reference category to estimate sensitivity and specificity.

**

The sensitivity and specificity of the outcome (SGA) measurement is assumed to be perfect (i.e. 1.0).