Table 1.
Tac1−/− mice biometric data.
| BW (g) | LV (mg) | LV/BW (mg/g) |
RV (mg) | RV/BW (mg/g) |
SBP (mmHg) | |
|---|---|---|---|---|---|---|
|
WT + Saline (n = 7) |
24.1 ± 0.6 | 74.4 ± 1.3 | 3.09 ± 0.11 | 25.0 ± 1.4 | 1.03 ± 0.05 | 100.1 ± 2.6 |
|
WT + ang II (n = 7) |
21.6 ± 0.6* | 68.7 ± 3.6 | 3.18 ± 0.14 | 18.5 ± 0.1* | 0.85 ± 0.07 | 107.3 ± 1.2 |
|
Tac1−/− + Saline (n = 6) |
22.9 ± 0.81 | 75.9 ± 9.0 | 3.31 ± 0.37 | 23.7 ± 4.7 | 1.03 ± 0.20 | 106.1 ± 0.2 |
|
Tac1−/− + ang II (n = 7) |
23.2 ± 1.1 | 79.8 ± 10.7 | 3.44 ± 0.35 | 20.8 ± 3.3 | 0.90 ± 0.16 | 121.2 ± 7.7*,†,‡ |
WT = wild type, BW = body weight, LV = left ventricle, RV = right ventricle, SBP = systolic blood pressure. Mean ± SD, *p < 0.05 vs WT Saline, †p < 0.05 vs WT ang II, ‡p < 0.05 vs Tac1−/− Saline.