Table 3.
List of secondary metabolite biosynthetic gene clusters in the S. rochei chromosome.
| Clustera | Product type | Location | Length (bp) | Possible metabolites |
|---|---|---|---|---|
| 1 | PKS-NRPS | SRO_0155-SRO_0157 | 12,171 | |
| 2 | Siderophore | SRO_0365-SRO_0370 | 8,474 | |
| 3 | Terpene | SRO_0471-SRO_0472 | 2,153 | 2-Methylisoborneol |
| 4 | PKS-NRPS | SRO_0501-SRO_0517 | 49,191 | |
| 5 | PKS | SRO_0730-SRO_0739 | 15,137 | |
| 6 | Lantipeptide-NRPS | SRO_0832-SRO_0848 | 34,433 | |
| 7 | PKS-NRPS | SRO_1003-SRO_1008 | 13,813 | |
| 8 | NRPS-Lantipeptide | SRO_1184-SRO_1189 | 11,055 | |
| 9 | Terpene | SRO_1200-SRO_1204 | 6,711 | Hopene |
| 10 | NRPS | SRO_1300-SRO_1346 | 70,044 | |
| 11 | NRPS | SRO_1551-SRO_1557 | 21,989 | |
| 12 | PKS-NRPS | SRO_1613-SRO_1615 | 11,979 | |
| 13 | Terpene | SRO_1735-SRO_1737 | 4,337 | Geosmin |
| 14 | Azoxyalkene and type I PKS | SRO_1819-SRO_1850 | 36,010 | KA57-A |
| 15 | Siderophore | SRO_2036-SRO_2038 | 4,744 | |
| 16 | NRPS | SRO_2051-SRO_2053 | 5,458 | |
| 17 | NRPS | SRO_2500-SRO_2506 | 9,881 | |
| 18 | Terpene | SRO_2585-SRO_2586 | 2,410 | Albaflavenone |
| 19 | Butyrolactone | SRO_3382 | 932 | |
| 20 | NRPS-Lantipeptide | SRO_3845-SRO_3849 | 6,875 | |
| 21 | Type II PKS | SRO_4037-SRO_4044 | 7,077 | Spore pigment |
| 22 | Siderophore | SRO_4684-SRO_4688 | 5,997 | |
| 23 | Melanin | SRO_4761-SRO_4762 | 1,446 | Melanin |
| 24 | Ectoine | SRO_5592-SRO_5595 | 3,165 | 5-Hydroxyectoine |
| 25 | Type I PKS | SRO_6166-SRO_6168 | 12,248 | |
| 26 | Type III PKS | SRO_6250-SRO_6251 | 2,284 | |
| 27 | NRPS | SRO_6287-SRO_6291 | 9,037 | |
| 28 | NRPS | SRO_6304-SRO_6312 | 46,390 | |
| 29 | Type I PKS (Iterative) | SRO_6377-SRO_6381 | 12,789 | |
| 30 | Pseudosugar | SRO_6636-SRO_6646 | 12,173 | |
| 31 | NRPS | SRO_7209-SRO_7215 | 44,813 | |
| 32 | Type I PKS | SRO_7221-SRO_7235 | 81,482 | Pentamycin |
| 33 | Type I PKS (Iterative) | SRO_7329-SRO_7331 | 9,456 | |
| 34 | NRPS | SRO_7379-SRO_7381 | 3,029 | |
| 35 | Terpene | SRO_7452-SRO_7458 | 8,979 | Carotenoid |
aSecondary metabolite gene clusters were predicted by 2nd Find and antiSMASH. The range of gene clusters for unknown secondary metabolites was estimated on the basis of putative functions of gene products.