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. 2019 Jul 29;9:10956. doi: 10.1038/s41598-019-47482-0

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(a) Experimental schedule, and double immunofluorescent analysis in the ipsilateral striatum of the pMX-ASN group for GFP/Dcx or GFP/NeuN at 24 d (b) and 52 d (c) after tMCAO. High-power images of GFP/Dcx double-positive cells (arrows in b). Some GFP/NeuN double-positive cells (arrows in c) showing synapse-like structures (arrowheads). The boxed area in (b,c) indicates the field shown in each right panel. (d) Percentage of neuronal conversion in GFP-positive cells 5 d, 10 d, 24 d and 52 d after tMCAO.