. Author manuscript; available in PMC: 2020 Jun 5.

Published in final edited form as: Hum Hered. 2019 Jun 5;83(6):315–332. doi: 10.1159/000499711

Table 3.

Number of loci detected with antagonistic (ANT) effects, i.e., opposite effect direction effects, in GxE analysis using the different dichotomous PA variables. Percentage of total loci detected with ANT in parentheses.

		SBP		DBP

	Joint 2 DF	Interaction 1 DF	Joint 2 DF	Interaction 1 DF

LQsplit	3 (50%)	6 (100%)	1 (33%)	3 (100%)
MEDsplit	11 (73%)	9 (100%)	4 (80%)	9 (100%)
SIEE	0 (0%)	2 (25%)	4 (80%)	5 (62%)

Abbreviations: SBP, systolic blood pressure; DBP, diastolic blood pressure; LQsplit, created by splitting Quantitative by the lower quartile of its distribution; MEDsplit, created by splitting Quantitative by the median of its distribution; SIEE, created by selecting individuals with Quantitative values in the lower and upper quartiles and excluding individuals intermediate between the lower and upper quartile.