Figure 4.

Effect of obesity on Cl-HCO₃ exchange in intestinal epithelial cells. DIDS-sensitive and HCO₃-driven ³⁶Cl uptake was significantly increased in villus-cell BBMVs of OZRs as compared with LZRs (A), TOM vs. C57BL/6 (B), and obese human small intestine vs. normal (C). For all experiments, n represents different studies performed with intestinal cells isolated from different host each time; n = 4. *P<0.01.