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α2-3-Sialyllactose exhibits 2 different binding modes to proteins. A) α2-3-Sialyllactose binds to loops formed from a β-sheet core in T. cruzi trans-sialidase (PDB 1s0i). B) α2-3-Sialyllactose binds to a raft of antiparallel β-sheets on the galectin-8 protein surface (PDB 4wvw).
