Table 1. Patient characteristics by human papillomavirus (HPV) status.
Numbers (%) | |||
---|---|---|---|
Total | HPV-positive | HPV-negative | |
Study population | 121 | 98 (81.0%) | 23 (19.0%) |
Gender | |||
Male | 87 (71.9%) | 74 (85.1%) | 13 (14.9%) |
Female | 34 (28.1%) | 24 (70.6%) | 10 (29.4%) |
OPC subsite | |||
Tonsillar | 77 (63.6%) | 68 (88.3%) | 9 (11.7%) |
Base of the tongue | 32 (26.4%) | 26 (81.3%) | 6 (18.7%) |
Soft palate/pharyngeal wall | 12 (10.0%) | 4 (33.3%) | 8 (66.7%) |
T-stage | |||
1 | 26 (21.5%) | 24 (92.3%) | 2 (7.7%) |
2 | 54 (44.6%) | 46 (85.2%) | 8 (14.8%) |
3 | 20 (16.5%) | 17 (85%) | 3 (15%) |
4a | 14 (11.6%) | 8 (57.1%) | 6 (42.9%) |
4b | 7 (5.8%) | 3 (42.9%) | 4 (57.1%) |
N-stage | |||
0 | 29 (24%) | 24 (82.8%) | 5 (17.2%) |
1 | 18 (14.9%) | 13 (72.2%) | 5 (27.8%) |
2a | 10 (8.3%) | 10 (100%) | 0 (0%) |
2b | 48 (39.7%) | 42 (87.5%) | 6 (12.5%) |
2c | 11 (9.1%) | 4 (36.4%) | 7 (63.6%) |
3 | 5 (4.1%) | 5 (100%) | 0 (0%) |
M-stage | |||
0 | 117 (96.7%) | 95 (81.2%) | 22 (18.8%) |
1 | 4 (3.3%) | 3 (75%) | 1 (25%) |
Clinical stage | |||
I | 3 (2.5%) | 2 (66.7%) | 1 (33.3%) |
II | 14 (11.6%) | 13 (92.9%) | 1 (7.1%) |
III | 20 (16.5%) | 15 (75%) | 5 (25%) |
IVA | 70 (57.9%) | 59 (84.3) | 11 (15.7%) |
IVB | 10 (8.3%) | 6 (60%) | 4 (40%) |
IVC | 4 (3.3%) | 3 (75%) | 1 (25%) |
Smoking habits | |||
Smokers (or recently stopped) | 45 (37.1%) | 29 (64.4%) | 16 (35.6%) |
Ex-smokers | 34 (28.1%) | 27 (79.4%) | 7 (20.6%) |
Never smoked | 42 (34.7%) | 42 (100%) | 0 (0%) |
Initial treatment intention | |||
Curative | 109 (90%) | 93 (85.3%) | 16 (14.7%) |
Palliative | 12 (10%) | 5 (41.7%) | 7 (58.3%) |
Survival | |||
Deceased during 3-year follow-up | 35 (28.9%) | 17 (48.6%) | 18 (51.4%) |
Died of OPC | 26 (21.5%) | 11 (42.3%) | 15 (57.7%) |