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. 2019 Jul 29;14(7):e0220534. doi: 10.1371/journal.pone.0220534

Table 1. Patient characteristics by human papillomavirus (HPV) status.

Numbers (%)
Total HPV-positive HPV-negative
Study population 121 98 (81.0%) 23 (19.0%)
Gender
Male 87 (71.9%) 74 (85.1%) 13 (14.9%)
Female 34 (28.1%) 24 (70.6%) 10 (29.4%)
OPC subsite
Tonsillar 77 (63.6%) 68 (88.3%) 9 (11.7%)
Base of the tongue 32 (26.4%) 26 (81.3%) 6 (18.7%)
Soft palate/pharyngeal wall 12 (10.0%) 4 (33.3%) 8 (66.7%)
T-stage
1 26 (21.5%) 24 (92.3%) 2 (7.7%)
2 54 (44.6%) 46 (85.2%) 8 (14.8%)
3 20 (16.5%) 17 (85%) 3 (15%)
4a 14 (11.6%) 8 (57.1%) 6 (42.9%)
4b 7 (5.8%) 3 (42.9%) 4 (57.1%)
N-stage
0 29 (24%) 24 (82.8%) 5 (17.2%)
1 18 (14.9%) 13 (72.2%) 5 (27.8%)
2a 10 (8.3%) 10 (100%) 0 (0%)
2b 48 (39.7%) 42 (87.5%) 6 (12.5%)
2c 11 (9.1%) 4 (36.4%) 7 (63.6%)
3 5 (4.1%) 5 (100%) 0 (0%)
M-stage
0 117 (96.7%) 95 (81.2%) 22 (18.8%)
1 4 (3.3%) 3 (75%) 1 (25%)
Clinical stage
I 3 (2.5%) 2 (66.7%) 1 (33.3%)
II 14 (11.6%) 13 (92.9%) 1 (7.1%)
III 20 (16.5%) 15 (75%) 5 (25%)
IVA 70 (57.9%) 59 (84.3) 11 (15.7%)
IVB 10 (8.3%) 6 (60%) 4 (40%)
IVC 4 (3.3%) 3 (75%) 1 (25%)
Smoking habits
Smokers (or recently stopped) 45 (37.1%) 29 (64.4%) 16 (35.6%)
Ex-smokers 34 (28.1%) 27 (79.4%) 7 (20.6%)
Never smoked 42 (34.7%) 42 (100%) 0 (0%)
Initial treatment intention
Curative 109 (90%) 93 (85.3%) 16 (14.7%)
Palliative 12 (10%) 5 (41.7%) 7 (58.3%)
Survival
Deceased during 3-year follow-up 35 (28.9%) 17 (48.6%) 18 (51.4%)
Died of OPC 26 (21.5%) 11 (42.3%) 15 (57.7%)