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. 2019 May 23;11(5):e4727. doi: 10.7759/cureus.4727

Table 2. A 19-year-old female with pseudohyperthyroidism due to self-prescribed 20 mg/day biotin for hair and nail changes in iron deficiency anemia and polycystic ovary syndrome.

Investigations Initial investigations Aug 30, 2018 On biotin Off biotin Normal values
Nov 22, 2018 Nov 24, 2018 24 hours after 48 hours after 72 hours after
TSH µIU/ml 0.86 0.04 0.05 1.04 1.11   0.27-4.2
FT4 ng/dl 1.63 3.23 3.48 2.55 2.30 1.04 0.93-1.7
FT3 pg/ml     4.01 2.24     1.21-4.18
TT4 µg/dl 14.00 22.12 20.17 10.30     5.1-14.1
TT3 ng/ml 0.9 4.21 4.56 1.56     0.8-2
Anti-TPO IU/ml     3.22       0-34
TRAb mIU/ml     0.68       <2
Roche Cobas e411 immunoassay. TSH: Thyroid-Stimulating Hormone, FT4: Free Thyroxine, FT3: Free Triiodothyronine, TT4: Total Thyroxine, TT3: Total triiodothyronine, Anti-TPO: Antithyroid Peroxidase, TRAb: Thyrotropin Receptor Antibody.