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PI3K pathway mutations and copy number aberrations present in cohort. Thirteen patients had PI3K pathway mutations or copy number aberrations. AMP indicates amplification and DEL indicates deletion.
| Patient | AKT1 | AKT2 | PI3KCA | PI3KCB | PI3KR1 | PI3KR3 | PTEN |
|---|---|---|---|---|---|---|---|
| 1 | N345K | ||||||
| 2 | H1047R | ||||||
| 3 | H1047R | ||||||
| 4 | H1047R | ||||||
| 5 | E542K | ||||||
| 6 | E542K | ||||||
| 7 | E17K | E542K | |||||
| 8 | E17K | E194D | |||||
| 9 | C60_I75dup | ||||||
| 10 | AMP | AMP | |||||
| 11 | V402_L413del | ||||||
| 12 | DEL | ||||||
| 13 | A151K |
