Table 2.
Patient Characteristics
| All | Dose Escalation | Expansion | |
|---|---|---|---|
| Number enrolled | 18 | 14 | 4 |
| Median Age, years (range) | 55 (42–81) | 53 (42–81) | 64 (42–69) |
| Gender, N (%) | |||
| - Female | 11 (61) | 7 (50) | 4 (100) |
| - Male | 7 (39) | 7 (50) | 0 |
| Performance Status, N (%) | |||
| - 0 | 8 (44) | 7 (50) | 1 (25) |
| - 1 | 7 (39) | 5 (36) | 1 (50) |
| - 2 | 3 (17) | 2 (14) | 1 (25) |
| Tumor Types, N (%) | |||
| - Colorectal | 5 (28) | 4 (36) | 0 |
| - Cervical | 3 (17) | 0 | 3 (75) |
| - Anal | 2 (11) | 1 (7) | 1 (25) |
| - Soft Tissue Sarcoma | 2 (11) | 2 (14) | 0− |
| - Esophageal | 1 (6) | 1 (7) | 0 |
| - HNSCC | 1 (6) | 1 (7) | 0 |
| - Lung | 1 (6) | 1 (7) | 0 |
| - Endometrial | 1 (6) | 1 (7) | 0 |
| - Pancreas | 1 (6) | 1 (7) | 0 |
| - Kidney | 1 (6) | 1 (7) | 0 |
| Prior lines of systemic therapy, N (%) | |||
| - 1 | 4 (22) | 2 (14) | 1 (50) |
| - 2 | 3 (17) | 2 (14) | 1 (25) |
| - 3 | 6 (28) | 4 (36) | 0 |
| - 4+ | 5 (33) | 5 (36) | 1 (25) |
| Prior radiation therapy, N (%) | |||
| - Yes | 12 (67) | 10 (71) | 1 (50) |
| - No | 6 (33) | 4 (29) | 2 (50) |