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. 2019 May 7;38(8):845–855. doi: 10.1016/j.healun.2019.05.001

Figure 3.

Figure 3

Acute cellular rejection (ACR) classification of bronchoalveolar lavage (BAL) cell pellet (CP) gene expression by classifier model. (a) Receiver operator characteristic (ROC) curve of classifier performance on 165 subject training set. (b) Classification scores (the predicted probability of ACR divided by 0.261) are plotted on the y axis for each subject. In the training set, the dashed line (score 1.0) denotes the classification threshold between ACR and no ACR classification. Transbronchial biopsy (TBBX) histopathology or infection diagnoses are provided for each subject on the x axis. Black closed circles represent chronic lung allograft dysfunction (CLAD)-free survivors. Gray triangles pointing up represent subjects developing CLAD within 1 year of sample. Gray triangles pointing down represent subjects who died within 1 year of sample. (c) ROC curve of classifier performance on the 54 subject testing set. (d) Classification scores in the 54 subject testing set. AUC, area under the curve.