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. 2019 May 7;38(8):845–855. doi: 10.1016/j.healun.2019.05.001

Table 3.

Gene Ontology: Top Biological Processes Enriched With ACR

Term Fold enrichment Genes p-value FDR
Immune response 9.8 CXCL12, CD27, FASLG, CTLA4, GZMB, GZMH 0.00028 0.0037
Adaptive immune response 24.1 SH2D1A, CTLA4, IFNG, KLRK1 0.00055 0.0071
T-cell receptor signaling pathway 44.3 CD27, CD3E, IFNG 0.00190 0.0250
Inflammatory response 8.7 CXCL13, CXCR3, CXCR6, CD27, AFAP1L2 0.00220 0.0290

ACR, acute cellular rejection; FDR, false discovery rate.