Fig. 2.
Brain angioarchitecture and BBB integrity are unaffected in α5-TKO mice under homeostatic conditions. a Representative 3D images of IB4 (green) staining in control and α5-TKO brains. b-d Quantifications of vessel density (b), vessel length (c), and branching index (d) in control and α5-TKO brains. n=3. Student’s t-test was used for statistical analyses. e Representative images of CD31 (green) and IgG (red) staining in control and α5-TKO brains. f-h Quantifications of IgG (f), Evans blue (g), and FITC-Dextran (h) levels in the brains of these mice. n=4. Student’s t-test was used for statistical analyses.