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. 2019 Jun 6;294(30):11354–11368. doi: 10.1074/jbc.RA118.007152

Figure 8.

Figure 8.

Peroxynitrite supports a metabolic reprogramming in human NF2-associated schwannoma cells. Peroxynitrite supports a metabolic shift in human MD-Schwann cells characterized by decreased oxidative phosphorylation and increased glycolysis and glutamine dependence. Dotted lines indicate mechanisms yet to be elucidated. Ox, oxidized protein; -Tyr-NO2, nitrotyrosine.