Figure 7.

Crystal packing of wtACMSD and H110A. A, previously published wtACMSD crystallized in the monoclinic space group (C121, PDB entry 2HBV) (1). B, wtACMSD crystallizes under new conditions (see “Experimental procedures”) in the orthorhombic space group (C222₁, PDB entry 6MGS). C, H110A under the same conditions as in B crystallized in the tetragonal space group (P4₂2₁2, PDB entry 6MGT). Unit cells are shown as gray boxes, asymmetric units are marked by color, and chain B for wtACMSD in B is shown at 50% transparency for clarity. His-110 or Ala-110 is highlighted in yellow.