TABLE 7.
CLSI disk diffusion QC ranges determined for cefepime (30 μg) and cefepime-enmetazobactam (30/20 μg) against relevant reference strains
| Reference strain | Cefepime-enmetazobactam |
Cefepime |
||||
|---|---|---|---|---|---|---|
| Inhibition zone diameter QC range (mm)a | No. of mm | % Of values in rangeb | Inhibition zone diameter QC range (mm) | No. of mm | % Of values in range | |
| E. coli ATCC 25922 | 32–38 | 7 | 97.1 | 31–37c | 7 | 97.1 |
| E. coli ATCC 35218 | 32–38 | 7 | 100.0 | 31–37 | 7 | 100.0 |
| E. coli NCTC 13353 | 27–33 | 7 | 100.0 | 6–15c ,d | 10 | 99.5 |
| K. pneumoniae ATCC 700603 | 26–32 | 7 | 98.3 | 23–29c | 7 | 99.8 |
| P. aeruginosa ATCC 27853 | 26–32 | 7 | 99.4 | 25–31c | 7 | 99.2 |
QC ranges were approved at the January 2019 meeting of the CLSI Subcommittee on Antimicrobial Susceptibility Testing.
Percentage of values in range determined from 480 replicates performed in eight laboratories.
Current CLSI QC range (35).
Excluding data from one laboratory (statistical outlier).