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. 2019 Jul 26;57(8):e00607-19. doi: 10.1128/JCM.00607-19

TABLE 7.

CLSI disk diffusion QC ranges determined for cefepime (30 μg) and cefepime-enmetazobactam (30/20 μg) against relevant reference strains

Reference strain Cefepime-enmetazobactam
Cefepime
Inhibition zone diameter QC range (mm)a No. of mm % Of values in rangeb Inhibition zone diameter QC range (mm) No. of mm % Of values in range
E. coli ATCC 25922 32–38 7 97.1 31–37c 7 97.1
E. coli ATCC 35218 32–38 7 100.0 31–37 7 100.0
E. coli NCTC 13353 27–33 7 100.0 6–15c ,d 10 99.5
K. pneumoniae ATCC 700603 26–32 7 98.3 23–29c 7 99.8
P. aeruginosa ATCC 27853 26–32 7 99.4 25–31c 7 99.2
a

QC ranges were approved at the January 2019 meeting of the CLSI Subcommittee on Antimicrobial Susceptibility Testing.

b

Percentage of values in range determined from 480 replicates performed in eight laboratories.

c

Current CLSI QC range (35).

d

Excluding data from one laboratory (statistical outlier).