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. Author manuscript; available in PMC: 2019 Jul 29.
Published in final edited form as: Nat Microbiol. 2018 Dec 3;4(2):328–338. doi: 10.1038/s41564-018-0309-1

Table 4 |.

SNP-based heritability of MIC for different antibiotics

hSNP2 hsingles2 hpairs2

PEN 0.830 0.203
TET 0.891 0.073
CFX 0.825 0.807 0.850
CIPRO 0.931 0.763 0.953
AZI 0.900 0.4970 0.712

Heritability was estimated on the whole dataset (n = 1,597) using a linear mixed model: hSNP2 estimated considering all common SNPs; hsingles2 was estimated considering significant loci only; and hpairs2 was estimated considering significant loci and significant epistatic pairs.