Fig. 3.

Femur diaphysis micro-CT (a–d), biomechanics (e, f), and femoral diaphyseal bone mass-strength relationships (g–h). a Cortical area; b cortical area per total area; c cortical thickness; d cortical volumetric BMD; e ultimate load; f bending rigidity; g, h linear regressions for ultimate load vs micro-CT-derived cortical area and volumetric BMD, respectively. Additional femur diaphysis micro-CT data are presented in Table 1. Data represent means ± SEM, n = 7–8/group. OVX, ovariectomy; GC, glucocorticoid (methyl-prednisolone); ABL5, abaloparatide 5 μg/kg/day; ABL25, abaloparatide 25 μg/kg/day. ^SP < 0.05 vs. sham, ^OP < 0.05 vs. OVX, ^GP < 0.05 vs. GC-OVX, and ⁵P < 0.05 vs. ABL5 by one-way ANOVA and Tukey’s post-test