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. 2019 Jul 23;10:1709. doi: 10.3389/fimmu.2019.01709

Table 2.

Binding assays of HLA-A*30:01 or -A*30:03 with peptide MTB and its mutants.

Name Sequencea Refoldingb
A*30:01 A*30:03
MTB QIMYNYPAM +
MTB-M9K QIMYNYPAK + +
MTB-M9R QIMYNYPAR +
MTB-M9Y QIMYNYPAY +
MTB-M9F QIMYNYPAF +
MTB-M9I QIMYNYPAI +
MTB-M9V QIMYNYPAV +
MTB-M9L QIMYNYPAL +
MTB-M9T QIMYNYPAT +
MTB-M9S QIMYNYPAS +
a

Underlined boldface residues are the substituted sites.

b

In the in vitro refolding assay, peptides that can help the HLA-A*30:01 or -A*30:03 H chain renature with human β2 microglobulin (β2m) are marked as +, otherwise as –.