Table 2.
Name | Sequencea | Refoldingb | |
---|---|---|---|
A*30:01 | A*30:03 | ||
MTB | QIMYNYPAM | – | + |
MTB-M9K | QIMYNYPAK | + | + |
MTB-M9R | QIMYNYPAR | + | – |
MTB-M9Y | QIMYNYPAY | – | + |
MTB-M9F | QIMYNYPAF | – | + |
MTB-M9I | QIMYNYPAI | – | + |
MTB-M9V | QIMYNYPAV | – | + |
MTB-M9L | QIMYNYPAL | – | + |
MTB-M9T | QIMYNYPAT | – | + |
MTB-M9S | QIMYNYPAS | – | + |
Underlined boldface residues are the substituted sites.
In the in vitro refolding assay, peptides that can help the HLA-A*30:01 or -A*30:03 H chain renature with human β2 microglobulin (β2m) are marked as +, otherwise as –.