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Ampkα deficiency abolished the protective effect of matrine in vivo. (A)–(D) Representative Western blot images and statistical results (n = 6). (E) The content of MDA and total SOD activity (n = 6). (F) Plasma levels cTnT and LDH (n = 6). (G) Heart function evaluated by echocardiography and hemodynamic analysis of mice (n = 8). (H) Statistical results of the HW/TL (n = 12). Values represent the mean±SEM. *P< 0.05 versus the matched groups.
