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. 2019 Jun 1;9(2):219–230. doi: 10.15171/apb.2019.025

Table 10 . Indonesian plants and/or their components that show chemopreventive activity targeting deregulating cellular energetics induced by cancer cells .

Molecular target Plant/compounds Reference(s)
HIF-1α (↓) Brusatol 120
GLUT1(↓) Curcumin 121
Brusatol 120
PDK1 (↓) Brusatol 120
ROS (↑) Brucein D 122, 123
Xanthorrhizol 124
Curcumin 125

HIF-1α: hypoxia-inducible factor-1α; GLUT1: Glucose transporter 1; PDK1: pyruvate dehydrogenase kinase 1; ROS: reactive oxygen species.

↓: indicates down-regulation of a protein and/or pathway;

↑: indicates up-regulation of a protein and/or pathway.