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. 2019 Jun 1;9(2):219–230. doi: 10.15171/apb.2019.025

Table 3. Indonesian plants and/or their components that show chemopreventive activity targeting cancers’ growth suppressors .

Molecular target Plant/compounds Reference(s)
p53 (↑) Brucea javanica (aqueous extract) 47
Thymoquinone 48
PTEN (↑) Thymoquinone 49
pRb(↑) Curcumin 50
Cdki (↑) Curcumin 50

PTEN: phosphatase and tensin homolog; pRb:  retinoblastoma protein; Cdki: cyclin-dependent kinase inhibitor.

↑: indicates up-regulation of a protein and/or pathway.