|
Advantages
|
Disadvantages
|
| Toxicity is less |
Mechanical resistance is less |
|
Enhanced Biocompatibility
|
Difficulty in controlling pore size |
|
Possess mucoadhesive character
|
May contract |
|
Possess stability
|
Electrospinning is difficult for pure chitosan |
|
Drug targeting is site-specific
|
Preparation by crosslinking can affect intrinsic properties of chitosan |
|
Therapeutic index of the drug is increased
|
Low solubility in neutral and alkaline pH |
|
Frequent, expensive and unpleasant dosing is prevented
|
Method of preparation must be changed according to the drug to be delivered |
