Table 3.
Intrinsic properties of small-diameter DRG neurons from adult WT and TRESK KO mice
| Diameter, μm | Capacitance, pF | Rin,MΩ | Vrest, mV | Rheobase, pA | AP threshold, mV | AP amplitude, mV | AP half-width, ms | AHP amplitude, mV | Cell number | |
|---|---|---|---|---|---|---|---|---|---|---|
| Small IB4-negative neurons | ||||||||||
| WT | 21.3 ± 0.5 | 22.0 ± 0.9 | 882 ± 135 | −56.7 ± 1.2 | 61 ± 9 | −15.8 ± 1.7 | 111.9 ± 3.0 | 4.7 ± 0.4 | −18.4 ± 1.5 | 16 |
| KO | 20.5 ± 0.5 | 19.6 ± 1.1 | 761 ± 83 | −55.9 ± 1.5 | 47 ± 6 | −17.9 ± 2.0 | 115.2 ± 2.0 | 4.2 ± 0.4 | −20.0 ± 1.2 | 18 |
| Small IB4-positive neurons | ||||||||||
| WT | 21.3 ± 0.7 | 21.9 ± 1.2 | 575 ± 86 | −57.7 ± 1.5 | 149 ± 19 | −14.3 ± 2.0 | 115.4 ± 2.2 | 5.9 ± 0.6 | −19.1 ± 1.2 | 17 |
| KO | 21.8 ± 0.7 | 24.3 ± 1.7 | 627 ± 81 | −54.7 ± 1.1 | 128 ± 17 | −11.4 ± 2.4 | 114.8 ± 2.9 | 5.7 ± 0.4 | −21.9 ± 1.5 | 19 |