Table 3.

Stratified analysis of the ACTB gene with DKD by age.

SNP	Age	Group	WT/HT/MT	Genotype OR (95% CI)a
				Additive model		Dominant model		Recessive model
			AA/AG/GG		Heterogeneity test		Heterogeneity test		Heterogeneity test
rs852423	≤70 years	Case	338/305/70	1.124 (0.959–1.318)	P = 0.994	1.147 (0.933–1.41)	P = 0.912	1.197 (0.837–1.712)	P = 0.854
		Control	387/324/66	P = 0.150		P = 0.193		P = 0.324
	>70 years	Case	378/343/76	1.125 (0.960–1.317)		1.166 (0.951–1.429)		1.140 (0.794–1.637)
		Control	378/295/60	P = 0.145		P = 0.139		P = 0.477
			TT/TC/CC		Heterogeneity test		Heterogeneity test		Heterogeneity test
rs852426	≤70 years	Case	426/240/47	1.130 (0.949–1.344)	P = 0.208	1.058 (0.857–1.306)	P = 0.047	1.815 (1.132–2.908)	P = 0.375
		Control	472/274/31	P = 0.170		P = 0.601		P = 0.013
	>70 years	Case	464/278/55	1.323 (1.116–1.568)		1.443 (1.168–1.782)		1.332 (0.866–2.048)
		Control	489/205/39	P = 0.001		P = 0.001		P = 0.192
			TT/TC/CC		Heterogeneity test		Heterogeneity test		Heterogeneity test
rs2966449	≤70 years	Case	386/270/57	1.143 (0.969–1.35)	P = 0.834	1.121 (0.911–1.380)	P = 0.336	1.446 (0.960–2.178)	P = 0.190
		Control	4336/296/45	P = 0.113		P = 0.280		P = 0.078
	>70 years	Case	424/319/54	1.172 (0.994–1.381)		1.296 (1.055–1.592)		0.959 (0.640–1.436)
		Control	438/244/51	P = 0.059		P = 0.013		P = 0.838

^aAdjusted for gender, smoking, drinking, BMI and diabetic duration, TG, TC, HDL-C and LDL-C.