Table 4.
Comparison of eGFR among the genotypes of ACTB.
| SNP | DKD Group | eGFR (mean ± SD) | P | ||
|---|---|---|---|---|---|
| rs852423 | AA | AG | GG | ||
| Case | 57.97 ± 18.26 | 59.67 ± 18.74 | 57.83 ± 18.74 | 0.203 | |
| Control | 83.02 ± 13.58 | 84.17 ± 13.37 | 82.11 ± 12.83 | 0.152 | |
| rs852426 | TT | TC | CC | ||
| Case | 58.46 ± 18.68 | 59.06 ± 18.26 | 58.74 ± 18.57 | 0.840 | |
| Control | 83.01 ± 13.82 | 84.34 ± 12.78 | 82.67 ± 12.51 | 0.189 | |
| rs2966449 | TT | TC | CC | ||
| Case | 57.88 ± 18.46 | 60.26 ± 18.53 | 56.23 ± 18.47 | 0.021a | |
| Control | 83.02 ± 13.35 | 84.39 ± 13.62 | 81.55 ± 13.04 | 0.065 | |
a
The average eGFR levels of the TT and CC genotypes of rs2966449 was significantly lower than that of TC genotype in DKD cases (P < 0.05 by SNK test).