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. 2019 Jul 25;13:2513–2532. doi: 10.2147/DDDT.S214454

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© 2019 Karimi et al.

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Effect of Thy, ThyNPMO, E, and ENPMO on nitric oxide (NO) production in NG and HG states. Bar graphs showing NO level (%) in olfactory ensheathing cells (OECs) exposed to normal glucose (NG), high glucose (HG), high mannitol (HM), NG plus Thymol (NG-Thy), HG plus Thymol (HG-Thy), NG plus Thymol polymeric nanoparticles modified by oleic acid (NG-ThyNPMO), HG plus Thymol polymeric nanoparticles modified by oleic acid (HG-ThyNPMO), NG plus extract (NG-E), HG plus Extract (HG-E), NG plus extract polymeric nanoparticles modified by oleic acid (NG-ENPMO), HG plus extract polymeric nanoparticles modified by oleic acid (HG-ENPMO). Data are expressed as mean±SEM. *p<0.01 vs NG and HM, **p<0.001 vs NG and HM, # # p<0.001 vs HG. $$ p<0.001 thymol vs ThyNPMO, ¥¥ p<0.001 E vs ENPMO.