Table 1.

Gene set enrichment using the MSigDB database.

Gene Set Name [# Genes (K)]	Description	# Genes in  Overlap (k)	k/K	p-value	FDR q-value
KEGG_CALCIUM_SIGNALING_PATHWAY [178]	Calcium signaling pathway	18		4.42 e−10	8.21 e−8
KEGG_CHEMOKINE_SIGNALING_PATHWAY [190]	Chemokine signaling pathway	16		5.56 e−8	5.17 e−6
KEGG_LONG_TERM_POTENTIATION [70]	Long-term potentiation	8		1.29 e−5	8.02 e−4
KEGG_MAPK_SIGNALING_PATHWAY [267]	MAPK signaling pathway	15		2.17 e−5	1.01 e−3
KEGG_HUNTINGTONS_DISEASE [185]	Huntington’s disease	12		3.56 e−5	1.33 e−3
KEGG_ALZHEIMERS_DISEASE [169]	Alzheimer’s disease	11		7.24 e−5	2.25 e−3
KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTER TERACTION [272]	Neuroactive ligand-receptor interaction	14		1.03 e−4	2.74 e−3
KEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SY_SYSTEM [76]	Phosphatidylinositol signaling system	7		1.8 e−4	3.76 e−3
KEGG_GNRH_SIGNALING_PATHWAY [101]	GnRH signaling pathway	8		1.82 e−4	3.76 e−3
KEGG_TIGHT_JUNCTION [134]	Tight Junction	9		2.56 e−4	4.57 e−3

Abbreviations: MSigDB, Molecular Signatures Database; KEGG, Kyoto Encyclopedia of Genes and Genomes; MAPK, mitogen-activated protein kinases;GnRH, gonadotropin-releasing hormone; FDR, false discovery rate.