Figure 5.

Association between neuromelanin in the substantia nigra pars compacta dorsal tier and nigrostriatal dopamine transporter binding. Scatterplots and simple linear regression showing positive relationships between neuromelanin contrast ratio in the SNc^dor and ¹¹C-PE2I BP_ND in the pre-commissural dorsal putamen (A), pre-commissural ventral putamen (B), pre-commissural caudate (C) and SNc^dor (D) in the clinically-defined most affected (filled red circles, solid line) and least affected sides (open circles, dashed line). Grey shaded areas represent 95% confidence intervals. **Significant result following Benjamini-Hochberg FDR correction for all correlational tests. *Significance at P < 0.05. BP_ND = non-displaceable binding potential; LA = least affected; MA = most affected.