Table 1.
Characteristics of the study population.
| Parameter | Healthy controls | Patients with cardiometabolic diseases | p value | |
|---|---|---|---|---|
| Without chronic wounds | With chronic wounds | |||
| Number of patients | 88 | 55 | 59 | — |
| Age (yrs.), median (range) | 63 (50-73) | 64 (49-81) | 65 (40-87) | 0.086K |
| Sex (F/M), n | 33/55 | 29/26 | 22/37 | 0.145χ2 |
| FG (mg/dL), mean (95% CI) | — | 159.5 (149-179) | 147.2 (105-189) | 0.591W |
| HbA1C (%), mean (95% CI) | — | 7.73 (7.2-8.2) | 7.98 (7-8.9) | 0.620t |
| CHOL (mg/dL), median (95% CI) | — | 168 (163-177) | 164 (147-175) | 0.162M |
| HDL (mg/dL), median (95% CI) | — | 44.5 (40-49) | 35 (32-44) | 0.008M |
| LDL (mg/dL), mean (95% CI) | — | 101 (91-112) | 89.8 (81-99) | 0.104W |
| TG (mg/dL), mean (95% CI) | — | 148.4 (129-171) | 126.7 (108-148) | 0.156t |
| Creatinine (mg/dL), mean (95% CI) | — | 0.98 (0.92-1.04) | 0.89 (0.78-1.02) | 0.191W |
| HGB (g/dL), mean (95% CI) | — | 13.5 (13-13.9) | 12.9 (12.4-13.8) | 0.084t |
| CRP (mg/L), mean (95% CI) | — | 1.7 (1.3-2.3) | 19.6 (13.5-28.5) | <0.0001t |
yrs.: years; F/M: female-to-male ratio; SD: standard deviation; n: number of patients; FG: fasting glucose; HbA1C: glycated hemoglobin; CHOL: total cholesterol; HDL: high-density lipoprotein cholesterol; LDL: low-density lipoprotein cholesterol; TG: triglycerides; HGB: hemoglobin; CRP: C-reactive protein; KKruskal-Wallis H test; WWelch test; χ2chi-squared test; t t-test for independent samples; MMann-Whitney U test.