Table 2.
Correlation pattern between intermediates in the arginine/NO pathway and cytokines, chemokines, and growth factors.
Cytokine | Arg | Cit | ADMA | SDMA (log) | Arg/ADMA | Arg/SDMA |
---|---|---|---|---|---|---|
FGF2 | 0.13 | -0.29 | -0.17 | -0.28 | 0.21 | 0.27 |
G-CSF | 0.12 | -0.35∗ | -0.27 | -0.37∗ | 0.42‡ | 0.41‡ |
GM-CSF (log) | 0.06 | -0.39∗ | -0.36∗ | -0.42‡ | 0.39∗ | 0.36∗ |
IL-1β | 0.10 | -0.27 | -0.27 | -0.36∗ | 0.38∗ | 0.35∗ |
IL-4 | 0.17 | -0.32∗ | -0.21 | -0.34∗ | 0.32∗ | 0.36∗ |
IL-6 (log) | 0.08 | -0.30 | -0.39∗ | -0.23 | 0.52† | 0.27 |
IL-8 | -0.06 | -0.36∗ | -0.30 | -0.34∗ | 0.28 | 0.23 |
MCP1 (log) | -0.07 | -0.24 | -0.10 | -0.25 | 0.10 | 0.20 |
MIP-1α | 0.07 | -0.07 | -0.16 | -0.20 | 0.23 | 0.22 |
PDGF (log) | 0.25 | -0.21 | -0.10 | -0.17 | 0.27 | 0.28 |
TNFα (log) | 0.14 | -0.31 | -0.32∗ | -0.38∗ | 0.46‡ | 0.40∗ |
VEGF-A (log) | -0.07 | -0.28 | -0.37∗ | -0.28 | 0.32∗ | 0.14 |
∗ p ≤ 0.05, ‡ p < 0.01, and † p < 0.001. Data were analyzed using the Pearson test and reported as correlation coefficients r.