Table 3.
Correlation pattern between intermediates in the arginine/NO pathway in patients with cardiometabolic diseases with and without chronic wounds.
| Metabolite | Arginine | Citrulline | ADMA | SDMA (log) | Arg/ADMA | Arg/SDMA |
|---|---|---|---|---|---|---|
| Arginine | — | -0.14 | -0.15 | 0.23 | — | — |
| Citrulline | 0.20 | — | 0.81† | 0.85† | -0.62† | -0.63† |
| ADMA | 0.45† | 0.69† | — | 0.84† | — | — |
| SDMA (log) | 0.28∗ | 0.63† | 0.68† | — | — | — |
| Arg/ADMA | — | -0.35‡ | — | — | — | |
| Arg/SDMA | — | -0.36‡ | — | — | — | — |
The right side of the table (in italics) presents correlations in patients without wounds; the left side (in a straight script) presents correlations in patients with chronic wounds. ∗ p ≤ 0.05, ‡ p < 0.01, and † p < 0.001. Data were analyzed using the Pearson test and reported as correlation coefficients r.