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. 2019 Jul 17;2019:6029876. doi: 10.1155/2019/6029876

Figure 1.

Figure 1

The hepatoprotective effects of ME in mice with acute alcohol injury. Mice were treated with 13 g/kg of alcohol and/or cotreated with 60 mg/kg of Sil or 200, 400, or 800 mg/kg of ME for 14 days. Histopathological analysis of (a) liver and (b) kidney analyzed with H&E staining (40x). In livers, arrows showed the inflammation infiltration and the fat droplet. In kidneys, arrows showed the inflammation infiltration and the swelling glomerulus. ME and Sil reduced the levels of (c) TG and (d) TC and (e) increased the levels of HDL in the livers of mice with alcohol-induced acute liver injury. Data are expressed as mean ± S.E.M. (n = 10). # p < 0.05 vs. control mice, p < 0.05, ∗∗ p < 0.01, and ∗∗∗ p < 0.001 vs. alcohol only treated mice. ME: M. esculenta, Sil: silybin.