Table 5.
Performance of 3 protein classifier. The cut-off was chosen (CEACAM5 > 4.92, WFDC2 > 75.57, TCL1A > 8.34) to best separate benign and cancer cases and LAC and CRC met cases
| Signature vs Benign | |||||
| Specificity | 1.00 | Benign | 68 | 0 | True |
| Sensitivity | 0.45 | Tumor | 79 | 65 | outcome |
| PPV | 1.00 | Predicted outcome | |||
| NPV | 0.46 | ||||
| Accuracy | 0.63 | ||||
| Signature vs CRC met | |||||
| Specificity | 0.82 | CRC met | 68 | 15 | True |
| Sensitivity | 0.45 | LAC | 79 | 65 | Outcome |
| PPV | 0.81 | Predicted outcome | |||
| NPV | 0.46 | ||||
| Accuracy | 0.59 | ||||
PPV Positive predictive value, NPV Negative predictive value, LAC Lung adenocarcinoma, CRC met colorectal metastasis