Skip to main content
. 2019 Jul 29;39(16):e00035-19. doi: 10.1128/MCB.00035-19

FIG 6.

FIG 6

Differential IL-2 production kinetics between murine and human T cells render murine cells vulnerable to splicing modulation early after activation. (A) Quantification of secreted IL-2 in EL4 cells (n = 2); (B) quantification of IL-2 levels at 20 h poststimulation with splicing inhibition by Pld B in the h 0 to 2, 4 to 6, and 8 to 20 time windows (mean ± SD; n = 4) in EL4 cells; (C) quantification of secreted IL-2 in Jurkat cells (n = 3); (D) quantification of IL-2 levels at 32 h poststimulation with splicing inhibition by Pld B in the h 0 to 2, 4 to 6, and 8 to 20 time windows (mean ± SD; n = 4) in Jurkat cells. mIL-2, mouse IL-2; hIL-2, human IL-2.