Table 2.
Comparison of variables in SSc-PAH patiens with UA below vs. above the median value for the cohort (6.3 mg/dL).
| UA < 6.3 mg/dL (n=32) | UA > 6.3 mg/dL (n = 50) | P value | |
|---|---|---|---|
| Age, years | 63 (14) | 62 (12) | NS |
| WHO FC (n III/IV (%)) | 25 (32) | 46 (62) | <0.01 |
| 6MWD (m) | 362 (102) | 320 (95) | 0.06 |
| RAP (mmHg) | 6 (3) | 8 (4) | <0.05 |
| mPAP (mmHg) | 33 (8) | 41 (12) | <0.01 |
| PVR (Wood units) | 5.4 (3.5) | 7.8 (5.4) | <0.05 |
| CO (L/min) | 5.1 (1.4) | 4.6 (1.7) | 0.17 |
| CI (L/min/m2) | 2.9 (0.9) | 2.6 (0.8) | 0.12 |
Values are given as mean (SD) unless otherwise specified.
WHO FC, World Health Organization functional class; 6MWD, 6-min walk distance; RAP, right atrial pressure; mPAP, mean pulmonary arterial pressure; PCWP, pulmonary capillary wedge pressure; CO, cardiac output; CI, cardiac index; PVR, pulmonary vascular resistance.