Table 3.
Frequencies of the genotype and allele of NLRP1 polymorphisms between cases and controls in the Chinese Han population.
| SNP | Cases (N = 510) n (%) | Controls (N = 531) n (%) | OR (95% CI) | p | pc (n = 2) |
|---|---|---|---|---|---|
| rs11651270 | |||||
| Genotype | |||||
| CC | 23 (4.51) | 30 (5.65) | 0.677 (0.385-1.191) | 0.174 | 0.348 |
| CT | 145 (28.43) | 199 (37.48) | 0.643 (0.494-0.838) | 0.001∗ | 0.002∗ |
| TT | 342 (67.06) | 302 (56.87) | — | — | — |
| Allele | |||||
| C | 191 (18.73) | 259 (24.39) | 0.714 (0.579-0.882) | 0.002∗ | 0.004∗ |
| T | 829 (81.27) | 803 (75.61) | — | — | — |
| rs2670660 | |||||
| Genotype | |||||
| GG | 14 (2.75) | 16 (3.01) | 0.823 (0.396-1.712) | 0.602 | — |
| GA | 123 (24.12) | 164 (30.89) | 0.706 (0.536-0.930) | 0.013∗ | 0.026∗ |
| AA | 373 (73.14) | 351 (66.10) | — | — | — |
| Allele | |||||
| G | 151 (14.80) | 196 (18.46) | 0.768 (0.609-0.968) | 0.025∗ | 0.050 |
| A | 869 (85.20) | 866 (81.54) | — | — | — |
SNP: single-nucleotide polymorphisms; OR: odds ratio; 95% CI: 95% confidence intervals; pc: p value after correction for multiple comparisons.