. 2019 Jul 30;7:111. doi: 10.1186/s40478-019-0764-9

Table 5.

A statistical comparison of protein levels in the caudate nucleus of HD patients and non-HD individuals from the NIH NeuroBioBank

	Mann-Whitney^a	t-test^b	Multiple linear regression^c
Δtau314	p = 0.027	p = 0.041	p = 0.082
T-tau	p = 0.00055	p = 0.0031	p = 0.038
Δtau314:T-tau	p = 0.0013	p = 0.00064	p = 0.0041
GAPDH	p = 0.15	p = 0.29	p = 0.29
Casp2:GAPDH	p = 0.0036	p = 0.0035	p = 0.0070

^aThe two-tailed, unpaired Mann-Whitney test was performed

^bThe two-tailed, unpaired t-test with Welch’s correction was performed on the log transformed outcomes

^cMultiple linear regression was used to analyze the log transformed outcomes of protein levels with adjustment for age at death, sex and PMI of brain tissue harvest